Stent coatings comprising hydrophilic additives
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsStephen D. Pacetti, Yiwen Tang
Life of this patent
Estimating the term…
Abstract
A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating system.
Claims22
An implantable medical device comprising a coating, the coating including
- a mixture of at least one poly(meth)acrylate comprising a macromolecular chain and at least one polyalkylene glycol comprising a macromolecular chain,
- wherein a physically entangled or interpenetrating system formed of the macromolecular chains of the poly(meth)acrylate and the polyalkylene glycol,
- wherein the poly(meth)acrylate has a number average molecular weight (Mn) between about 50,000 and about 1,000,000 Daltons, and
- wherein the polyalkylene glycol has a Mn between about 5,000 and about 100,000 Daltons.
An implantable medical device comprising a coating, the coating including a mixture of at least one hydrophobic polymer comprising a macromolecular chain and at least one polymeric hydrophilic polymer comprising a macromolecular chain,
- wherein a physically entangled or interpenetrating system formed of the macromolecular chains of the hydrophobic polymer and the hydrophilic polymer,
- wherein the hydrophobic polymer has a number average molecular weight (Mn) between about 50,000 and about 1,000,000 Daltons, and
- wherein the hydrophilic polymer has a Mn between about 5,000 and about 100,000 Daltons.
An implantable medical device comprising a coating, the coating including a mixture of at least one hydrophobic polymer and at least one polymeric hydrophilic compound, wherein the macromolecular chains of the hydrophobic. polymer and the hydrophilic compound form a physically entangled or interpenetrating system, and
- wherein the hydrophobic polymer comprises poly(meth)acrylates, vinyl polymers, atactic polypropylene, halogenanated polymers, polymers having urethane groups, polybutyrals, nylon, silicones, polycarbonate, or polysulfone.
Dependencies are inferred from the claim text.