Methods and apparatus for intraluminal deposition of hydrogels
AssigneeIncept, LLC
InventorsAmarpreet S. Sawhney, John Spiridigliozzi
Life of this patent
Estimating the term…
Abstract
Methods and apparatus of forming hydrogel systems in situ are provided using a delivery system configured to deliver two or more fluent prepolymer solutions without premature crosslinking. The delivery system comprises separate first and second lumens coupling first and second inlet ports and first and second outlet ports, respectively, and may include a balloon, flexible distal region, mixing chamber or steerable distal end. Multi-component hydrogel systems suitable for use with the inventive methods and apparatus are also described.
Claims10
A system for sealing a puncture that passes through a patient's skin and through a wall of a lumen of an artery or vein of the patient, the system comprising:
- an occlusive element adapted to seal the lumen wall, so as to seal the lumen from the puncture;
- a delivery device comprising first and second inlet ports in fluid communication with a delivery conduit, the delivery conduit in fluid communication with an outlet port adapted to allow flowable materials introduced through the first and second inlet ports to exit the delivery device, the delivery conduit including a mixing chamber positioned so that flowable materials introduced through the first and second inlet ports are mixed prior to exiting the delivery device;
- a first container adapted for selective fluid communication with the first inlet port;
- and
- a second container adapted for selective fluid communication with the second inlet port.
A system for sealing a puncture that passes through a patient's skin and through a wall of a lumen of an artery or vein of the patient, the system comprising:
- means for sealing the lumen wall so as to seal the lumen from the puncture;
- means for holding a first flowable material;
- means for holding a second flowable material;
- means for delivering the first and the second materials into the puncture when the means for sealing has sealed off the lumen, the delivery means causing a mixing of the first and second materials prior to their delivery into the puncture, the first and second materials being crosslinkable with each other upon mixing to form a crosslinked structure.
A kit for sealing a puncture that passes through a patient's skin and through a wall of a lumen of an artery or vein of the patient, the kit comprising:
- an occlusive element adapted to seal the lumen wall so that the lumen is sealed off from the puncture;
- a delivery device comprising first and second inlet ports fluidly connected to a delivery conduit, the delivery conduit in fluid communication with an outlet port adapted to allow flowable materials introduced through the first and second inlet ports to exit the delivery device, the delivery conduit including a mixing chamber such that flowable materials introduced through the first and second inlet ports are mixed together prior to exiting the delivery device;
- a first container holding a first material, the first container removably attachable to the delivery device such that the contents of the first container may enter through the first inlet port;
- and
- a second container holding a second material, the second container removably attachable to the delivery device such that the contents of the second container may enter through the second inlet port, the first and second materials being crosslinkable with each other when mixed to form a crosslinked structure,
- wherein the delivery system is adapted to be positioned with the two inlet ports outside of the patient while the outlet port opens into the puncture and the occlusive element seals the vessel lumen.
Dependencies are inferred from the claim text.