Safe and effective biofilm inhibitory compounds and health-related uses thereof
AssigneeCernofina, LLC
InventorsRandall S. Alberte, Richard C. Zimmerman
Life of this patent
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Abstract
The present invention provides compounds and materials that reduce the accumulation of microorganisms a surface, by interfering with the attachment of the organisms to the surface. The compounds and materials are thus useful in preventing the formation of biofilms on surfaces in health-related environments. By preventing the formation of biofilms, the compounds formulated according to the present invention can be used in the fabrication of grafts, implants, medical devices in order to prevent infection thereof. The compounds formulated according to the present invention display an additional anticoagulant property, permitting their use in settings where decrease in blood coagulability is desirable.
Claims7
A coating comprising an effective amount of a compound represented by general structure 1:
- wherein
- X represents —OH, F, Cl, or Br;
- Y represents O;
- Z represents 4-(2-methylpropyl)phenyl, 4-(1,1-dimethylethyl)phenyl, 4-(1,1-dimethylpropyl)phenyl, 4-pentylphenyl, 4-(1-methyl-1-phenylethyl)phenyl, or 4-(1-methylheptyl)phenyl;
- wherein when the coating is applied to a surface of an article the coating releases the compound and wherein the coating comprises a phenolic resin, silicone polymer, epoxy resin, polyamide resin, vinyl resin, elastomer, acrylate polymer, silicone resin, polyester, chlorinated rubber, polyurethane, latex, or fluoropolymer.
Dependencies are inferred from the claim text.