Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections
AssigneesPolydex Pharmaceuticals Ltd., Rush-Presbyterian-St. Luke's Medical Center
InventorsLourens J. D. Zaneveld, Robert A. Anderson, Thomas C. Usher
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Abstract
A method for treating and preventing various infections, including papilloma virus and fungal and parasitic infections is provided. In particular, an effective amount of a sulfated polysaccharide, such as cellulose sulfate and dextran sulfate are administered to prevent and treat these infections. The invention also relates to use of these compounds for the prevention and inhibition of malignant epithelial lesions associated with papilloma virus, such as cervical cancer.
Claims42
A method of treating papilloma virus infection in a subject in need of such treatment comprising administering an effective amount of a sulfated polysaccharide to the subject wherein the sulfated polysaccharide is cellulose sulfate, dextran sulfate, dermatan sulfate, chondroitin sulfate, pentosan sulfate, fucoidin, mannan sulfate, dextrin sulfate, curdlan sulfate, chitin sulfate, heparin or heparin sulfate.
A method of inhibiting papilloma virus infection in a subject in need of such inhibition comprising administering an effective amount of a sulfated polysaccharide to the subject wherein the sulfated polysaccharide is cellulose sulfate, dextran sulfate, dermatan sulfate, chondroitin sulfate, pentosan sulfate, fucoidin, mannan sulfate, dextrin sulfate, curdlan sulfate, chitin sulfate, heparin or heparin sulfate.
Dependencies are inferred from the claim text.