Apoptosis related polynucleotides, polypeptides, and antibodies
AssigneeHuman Genome Sciences, Inc.
InventorsJian Ni, Paul E. Young, Steven M. Ruben
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Abstract
The present invention relates to novel human apoptosis related polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human apoptosis related polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human apoptosis related polypeptides.
Claims20
An isolated nucleic acid molecule comprising a polynucleotide selected from the group consisting of:
- (a) a polynucleotide encoding amino acid residues 1 to 304 of SEQ ID NO:11;
- and
- (b) a polynucleotide comprising nucleotides 1 to 2045 of SEQ ID NO:2.
An isolated nucleic acid molecule comprising a polynucleotide selected from the group consisting of:
- (a) a polynucleotide encoding the amino acid sequence of the full-length polypeptide encoded by the cDNA clone contained in plasmid HLDOK36 in ATCC Deposit No. PTA161;
- and
- (b) a polynucleotide comprising the cDNA clone contained in plasmid HLDOK36 in ATCC Deposit No. PTA161.
Dependencies are inferred from the claim text.