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US 7,078,036 B2Granted
Modulation of cholesteryl ester transfer protein (CETP) activity
AssigneeAvant Immunotherapeutics, Inc.
InventorsCharles W. Rittershaus, Lawrence J. Thomas
Life of this patent
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Abstract
This invention relates to peptides comprising a helper T cell epitope portion and a B cell epitope portion for eliciting an immune response against endogenous cholesteryl ester transfer protein (CETP) activity, to prevent or treat cardiovascular disease, such as atherosclerosis.
Claims10
A method for treating or preventing atherosclerosis in a human or animal comprising administering to said human or animal an antigenic vaccine peptide comprising a universal helper T cell epitope portion linked to a B cell epitope portion, wherein said B cell epitope portion comprises a B cell epitope of CETP.
Dependencies are inferred from the claim text.