Ultrasound imaging and treatment
AssigneeImarx Therapeutics, Inc.
InventorEvan C. Unger
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AssigneeImarx Therapeutics, Inc.
InventorEvan C. Unger
Estimating the term…
Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly usefull for example, in ultrasonic imaging applications and in therapeutic drug delivery systems. Gas, gaseous precursors and perfluorocarbons are presented as novel potentiators for ultrasonic hyper-thermia. The gas, gaseous precursors and perfluorocarbons which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased tissues. When therapeutic ultrasonic energy is applied to the diseased region heating is increased because of the greater effectiveness of sound energy absorption caused by these agents.
A method for an ultrasound treatment of a patient in need of such treatment, comprising administering, intra-arterially, to said patient a composition comprising stabilized gas bubbles and a therapeutic agent, and applying ultrasound, to treat said patient, wherein the stabilized gas bubbles are formed by a gas or a gas precursor selected from a group consisting of perfluoropropane;
A method for an ultrasound treatment of a patient in need of such treatment, comprising administering, intra-arterially, to said patient a composition comprising a perfluorocarbon and a therapeutic agent, and applying ultrasound, to treat said patient, wherein the perfluorocarbon is selected from a group consisting of perfluoropropane, perfluorobutane, perfluoropentane, perfluorohexane, perfluorocyclobutene, perfluoro-1-butene, perfluoro-2-butene, perfluoro-2-butyne, perfluoropropylene, and combinations thereof.
Dependencies are inferred from the claim text.