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US 6,991,824 B2Granted
Expression of human milk proteins in transgenic plants
AssigneeVentria Bioscience
InventorsNing Huang, Raymond L. Rodriguez, Frank E. Hagie
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Abstract
The invention is directed to food and food additive compositions comprising one or more human milk proteins produced in the seeds of a transgenic plant and methods of making the same. The invention is further directed to improved infant formula comprising such food supplement composition.
Claims10
A nutritionally enhanced food comprising
- one or more plant-derived food ingredients, and
- as an additive, a seed composition containing a flour, extract, or malt obtained from mature monocot seeds, and wherein said flour, extract, or malt contains seed-produced human milk proteins in substantially unpurified form selected from
- (i) lysozyme or lactoferrin, and one or more seed-produced human milk proteins selected from the group consisting of lactoferricin, epidermal growth factor, insulin-like growth factor-1, lactadherin, kappa-casein, haptocorrin, lactoperoxidase, and alpha-1-antitrypsin, -or
- (ii) lysozyme and lactoferrin, and optionally one or more seed-produced human milk proteins selected from the group consisting of lactoferricin, epidermal growth factor, insulin-like growth factor-1, lactadherin, kappa-casein, haptocorrin, lactoperoxidase, and alpha-1-antitrypsin.
1 more element
An ingestible monocot-seed composition containing a flour, extract, or malt obtained from mature monocot seeds, and wherein said flour, extract, or malt contains one or more seed-produced human milk proteins in substantially unpurified form, selected from
- (i) lysozyme or lactoferrin, and one or more seed-produced human milk proteins selected from the group consisting of lactoferricin, epidermal growth factor, insulin-like growth factor-1, lactadherin, kappa-casein, haptocorrin, lactoperoxidase, and alphf-1-antitrypsin, or
- (ii) lysozyme and lactoferrin, and optionally one or more seed-produced human milk proteins selected from the group consisting of lactoferricin, epidermal growth factor, insulin-like growth factor-1, lactadherin, kappa-casein, haptocorrin, lactoperoxidase, and alpha-1-antitrypsin.
Dependencies are inferred from the claim text.