Fast curing compositions
AssigneeTyco Healthecare Gropu LP
InventorMark Roby
Life of this patent
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Abstract
Fast curing surgical adhesives and sealants contain an NCO-terminated hydrophilic urethane prepolymer derived from an aromatic diisocyanate and a polyol. Substantially all the aromatic diisocyanate used to prepare the NCO-terminated hydrophilic urethane prepolymer is in the para form. Optionally, the aromatic diisocyanate is substituted with at least one electron withdrawing group, such as, for example, a fluorine group.
Claims25
A tissue adhesive composition comprising at least one sterilized NCO-terminated hydrophilic urethane prepolymer derived from (a) an aromatic diisocyanate substantially all of which is in the para configuration substituted with at least one electron withdrawing group and (b) a polyol component.
A tissue adhesive composition comprising at least one sterilized NCO-terminated hydrophilic urethane prepolymer derived from (a) an aromatic diisocyanate substantially all of which is in the para configuration substituted with at least one fluorine group and (b) a polyol component comprising ethylene oxide.
A method comprising:
- applying an adhesive composition comprising at least one sterile NCO-terminated hydrophilic urethane prepolymer derived from (a) an aromatic diisocyanate substantially all of which is in the para configuration substituted with at least one electron withdrawing group and (b) a polyol component to tissue.
A method of preparing a tissue adhesive comprising reacting (a) an aromatic diisocyanate substantially all of which is in the para configuration and substituted with at least one electron withdrawing group with (b) a polyol component to a form a prepolymer;
- and sterilizing the resulting product.
Dependencies are inferred from the claim text.