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US 6,860,867 B2Granted
Method of interventional surgery
AssigneeThe Regents of the University of California
InventorsKirk Patrick Seward, Albert P. Pisano
Life of this patent
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Abstract
A method of interventional surgery is described. The method may include inserting an actuator within a body of a vascularized organism and positioning the actuator adjacent a target region within a vessel of the body. The actuator is operated to cause a needle thereof to move in a substantially perpendicular direction relative to a wall of the vessel to produce an opening therein. A therapeutic or diagnostic agent may be delivered by the needle to the target region via the opening in the vessel wall.
Claims21
A method of interventional surgery comprising:
- inserting an actuator within a body of a vascularized organism and stopping the actuator adjacent a target region within a vessel of the vasculature of the body, the actuator including an expandable section incorporating a needle, the actuator being operable between an unactuated condition in which the expandable section is in a furled state and an actuated condition in which the expandable section is in an unfurled state;
- causing the expandable section to change from the furled state to the unfurled state, to cause the needle to move in a substantially perpendicular direction relative to a wall of the vessel to produce an opening therein;
- and
- delivering a therapeutic or diagnostic agent from the needle to the target region via the opening in the wall of the vessel.
1 more element
A method of interventional surgery comprising:
- inserting an actuator within a body of a vascularized organism and stopping the actuator adjacent a target region within a vessel of the vasculature of the body, the actuator including an actuator body having a distal end and a proximal end, a central expandable section including a needle and located between the distal end and the proximal end, the actuator being operable between an unactuated condition in which the expandable section is in a furled state and an actuated condition in which the expandable section is in an unfurled state;
- and
- operating the actuator to cause the expandable section to change from the furled state to the unfurled state such that the needle moves in an approximately perpendicular direction relative to a central longitudinal axis of the actuator body from a position inside the actuator body to a position outside the actuator body.
A method of catheter-based interventional surgery comprising:
- inserting and manipulating a distal end of a catheter within a body of a vascularized organism, the distal end of the catheter including an actuator;
- positioning the actuator adjacent a target region of a vessel of the vasculature of the body and terminating movement of the distal end of the catheter;
- operating the actuator to cause an expandable section thereof to change from a furled state to an unfurled state such that a microneedle at the expandable section moves in a substantially perpendicular direction relative to a wall of the vessel, from a position inside a body of the actuator to a position outside the body of the actuator, to produce an opening in the wall of the vessel.
A method of interventional surgery comprising:
- inserting an actuator within a body and stopping the actuator adjacent a target region within a vessel of the vasculature of the body, the actuator being operable between an unactuated condition in which an expandable section thereof is in a furled state and an actuated condition in which the expandable section is in an unfurled state, and a plurality of needles at the expandable section;
- and
- operating the actuator to cause the expandable section to change from the furled state to the unfurled state such that the needles move in an approximately perpendicular direction relative to a central longitudinal axis of the actuator from a position inside the actuator to a position outside the actuator.
A method of interventional surgery comprising:
- inserting an actuator within a body of a vascularized organism and stopping the actuator adjacent a target region within a vessel of the vasculature of the body, the actuator including an expandable section, the actuator being operable between an unactuated condition in which the expandable section is in a furled state and an actuated condition in which the expandable section is in an unfurled state, and a needle at the expandable section;
- and
- operating the actuator to cause the expandable section to change from the furled state to the unfurled state such that the needle moves from a position inside the actuator to a position outside the actuator.
Dependencies are inferred from the claim text.