US 6,725,081 B2Granted

Intravascular radiation delivery device

AssigneesVolcano Therapeutics, Inc., The Cleveland Clinic Foundation

InventorsJay P. Ciezki, Eugene J. Jung, Jr., Eric J. Lee, Emin M. Tuzcu, James D. Savage, Martin S. Weinhous

Life of this patent

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Abstract

A device and method for precisely delivering dosage of radiation from a radiation source to a treatment site of a vessel is provided herein. In one embodiment, the device includes a catheter which inserts into a vessel lumen of the body. The catheter includes an adjuster section for altering a portion of the radiation emitting radially from the radiation source so that the radiation source delivers an asymmetrical radiation profile to the vessel. The device can also include a catheter supporter which inhibits rotational deformation in the catheter between a catheter distal end and a catheter proximal end. This allows the delivery section to be precisely rotated to properly position the adjuster section within the vessel lumen.

Claims11

Dependent claims

A device for delivering a radiation source proximate to a treatment site in a vessel, said device comprising:

a catheter for receiving a portion of said radiation source, said catheter being dimensioned to be partially positioned within the vessel;
an imager being secured to said catheter, wherein said imager provides an image of the vessel, when said radiation source is positioned within said catheter;
a controller providing a radiation treatment plan for at least a portion of the vessel based upon said image of the vessel from said imager, and
an adjuster section secured to said catheter wherein said adjuster section alters the intensity of a portion of the radiation emitting radially from said radiation source for the vessel to receive a radiation dose profile which is substantially asymmetric relative to said radiation source, and further wherein said adjuster section alters the intensity of the radiation emitting from said radiation source to establish at least two equidistant, diametrically opposed points relative to said radiation source on said radiation dose profile for a difference in radiation dose to be between one percent and ninety-nine percent.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 09/876,481Filed 6 Jun 2001 · division
Priority: 28 Mar 1997
Published: US 2001/0027261 A14 Oct 2001
Granted: 20 Apr 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification3 codes

A61N 5/1002
Using radiation sources introduced into or applied onto the body; brachytherapy: intraluminal radiation therapy
A61N 2005/1005
Intraluminal radiation therapy: with asymmetrical radiation pattern
A61N
Electrotherapy

Family

Application08/827,489Parent of this continuation-in-part · filed 28 Mar 1997
Application09/118,308Parent of this division · filed 16 Jul 1998
US 6,033,357 AParent of this continuation-in-part · filed 7 Mar 2000
US 2001/0027261 A1Pre-grant publication · published 4 Oct 2001
US 6,309,339 B1Parent of this division
Application09/118,308Parent of this continuation-in-part
US 6,725,081 B2This patent

From the US filing history. Foreign family members aren’t listed.

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