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US 6,723,740 B2Granted
Activator of PPAR delta
AssigneeSmithKline Beecham Corporation
InventorsEsther Yu-Hsuan Chao, Curt Dale Haffner, Millard Hurst Lambert, III, Patrick Reed Maloney, Michael Lawrence Sierra, Daniel David Sternbach, Marcos Luis Sznaidman, Timothy Mark Willson, Huaqiang Eric Xu
Life of this patent
Estimating the term…
Abstract
Compounds of Formula (I) are disclosed. These compounds selected activators of human PPAR delta.
Claims1
A method for lowering triglycerides in a subject comprising the administration of a therapeutic amount of a hPPAR delta agonist of Formula (I)
- wherein
- X represents a COOH (or a hydrolysable ester thereof);
- X1 is O or S;
- X2 represents O or S;
- R1 and R2 independently represent H, CH3, OCH3, or halogen,
- n is 1 or 2,
- one of Y and Z is N and the other is S or O;
- y represents 1 or 2;
- each R3 independently represents CF3 or halogen.
6 more elements
Dependencies are inferred from the claim text.