Coated, platform-generating tablet

A method for administering an active ingredient, comprising:

• providing a tablet comprising a core having an active ingredient and an expandable material that expands upon exposure to aqueous environment, the core surrounded by an outer rate release modifying membrane that ruptures in a subject's gastrointestinal tract, the tablet having a belly band comprising the active ingredient;
• and
• administering the tablet to the subject.

A method for administering an active ingredient, comprising:

• providing a tablet, the tablet comprising a core comprising an active ingredient and an expandable material that expands upon exposure to an aqueous environment, an outer rupturable rate release modifying membrane, that ruptures in a subject's gastrointestinal tract, the tablet providing active ingredient release over at least a 16-hour period, and a belly band comprising the active ingredient;
• and
• administering the tablet to the subject.

A tablet, comprising:

• a core having at least one active ingredient, a mixture of expandable materials, or greater than 25% by weight of an expandable material based upon total core weight, the expandable material or materials expanding upon exposure to an aqueous environment, and a belly band comprising the at least one active ingredient;
• and
• an outer rupturable coating surrounding the core that ruptures in a subject's gastrointestinal tract, the coating comprising a rate release modifying membrane and a film modifier.

A method for administering an active ingredient, comprising:

• providing a tablet which exhibits a lag time for active ingredient dissolution from a core, the tablet comprising a core having an expandable material which expands upon exposure to an aqueous environment, at least one active ingredient, a belly band comprising the at least one active ingredient and an outer rupturable coating surrounding the core comprising a rate release modifying membrane and a film modifier;
• and
• administering the tablet to a subject, the tablet thereafter undergoing hydration so that, during hydration of the tablet, the core swells and ruptures the rate release modifying membrane in a subject's gastrointestinal tract, which breaks away from part of the tablet and exposed portions of the core, and remains attached to portions of the tablet providing a support platform for at least two hours when tested in vitro after initial rupture of the rate release modifying membrane occurs.

A tablet, comprising:

• a core having at least one active ingredient, and a mixture of expandable materials, or greater than 25% by weight of an expandable material based upon total core weight, the expandable material or materials expanding upon exposure to an aqueous environment, and a belly band comprising the at least one active ingredient;
• and
• an outer rupturable coating that ruptures in a subject's gastrointestinal tract.

A tablet, comprising a core having at least one active ingredient, a mixture of expandable materials, or greater than 25% by weight of an expandable material based upon total core weight, the expandable material or materials expanding upon exposure to an aqueous environment, and a belly band comprising the at least one active ingredient, where dissolution of the active ingredient is approximately zero order following an active ingredient dissolution lag time of from about 0.5 hour to about 6 hours.