PTFE vascular graft and method of manufacture

A multi-layered ePTFE graft comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material comprises multiple layers having resealable properties.

A multi-layered ePTFE graft comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material is augmented with a pre-sintered fluoropolymer bead wrap.

A multi-layered ePTFE graft comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material is augmented with a wire support coil.

A multi-layered ePTFE graft comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material is a self-sustained tubular structure.

A multi-layered ePTFE vascular graft useful for repeated hemoaccess comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material is selected from the group consisting of sheet, film, yarn, thread, mono-filament wrap, multi-filament wrap, tube, solvent-spun elastomeric fibers, helically-wound tape, and combinations thereof.

A multi-layered ePTFE vascular graft useful for repeated hemoaccess comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material is selected from the group consisting of thermoplastic elastomers, silicones, silicone rubbers, synthetic rubbers, polyurethanes, polyethers, polyesters, polyamides, fluoropolymers and combinations thereof.

A multi-layered ePTFE vascular graft useful for repeated hemoaccess comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material is a self-sustained tubular structure.

A multi-layered ePTFE vascular graft useful for repeated hemoaccess comprising:

• a first ePTFE tubular structure having a first porosity;
• a second ePTFE tubular structure having a different porosity than said first porosity, said second ePTFE tubular structure being disposed externally about said first ePTFE tubular structure;
• and
• a self-sealing material interposed between said first and second ePTFE tubular structures,
• wherein said self-sealing material comprises multiple layers having resealable properties.