Methods for treatment of aneurysms

A method of strengthening a vessel wall having an adventitial area in an area of an aneurysm of a subject comprising:

• administering a therapeutically effective amount of a photoactivatable agent to a subject, such that the agent is taken up by at least one layer of the vessel wall of the aneurysm;
• applying energy to a target region of the vessel wall in an area of the aneurysm, such that the photoactivatable agent is activated to strengthen the vessel wall;
• and
• increasing an adventitial area of the vessel wall.

A method for increasing an adventitial area of a blood vessel wall in an area of an aneurysm comprising:

• recognizing that increasing an adventitial area of a blood vessel strengthens the blood vessel;
• administering a therapeutically effective amount of a photoactivatable agent to a subject, such that the agent is taken up by the adventitial area of the vessel in an area of the aneurysm;
• applying energy to a target region of the blood vessel wall so that the photoactivatable agent is activated;
• and
• increasing the adventitial area of the vessel in an area of the aneurysm.

A method for treating an aneurysm by increasing an adventitial area of a blood vessel in an area of an aneurysm comprising:

• administering a therapeutically effective amount of a photoactivatable agent to a subject, such that the agent is taken up by an adventitial area of the blood vessel in an area of the aneurysm;
• applying energy to the site of the aneurysm to react within the photoactivatable agent;
• and
• increasing an adventitial area in the area of the aneurysm.