Substances having antiobese and visceral fat-reducing functions and utilization thereof
AssigneeJaniftec, Inc.
InventorsYoshitaka Nadachi, Kenji Koga, Masayuki Mizuno
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Abstract
The present invention is substances comprising coupling isomerized highly unsaturated fatty acids and/or their derivatives having an activity of specifically promoting the uncoupling respiration of mitochondria (MC) and proton leak in the MC inner membrane in cells of the main tissues producing nonshivering thermogenesis (nST), skeletal muscles, white adipose tissue (WAT) and brown adipose tissue (BAT).
Claims16
A method for inhibiting the accumulation of visceral fat in a mammal, comprising administering to the mammal a component of coupling at least one of isomerized highly unsaturated fatty acid or a derivative thereof, which has at least one activity of specifically accelerating the uncoupling respiration of mitochondria and accelerating proton leak in the mitochondrial inner membrane of one or more of a tissue of the mammal which produces nonshivering thermogenesis, skeletal muscle, white adipose tissue, and brown adipose tissue.
A method for reducing visceral fat in a mammal, comprising administering to the mammal a component of coupling at least one of isomerized highly unsaturated fatty acid or a derivative thereof, which has at least one activity of specifically accelerating the uncoupling respiration of mitochondria and accelerating proton leak in the mitochondrial inner membrane of one or more of a tissue of the mammal which produces nonshivering thermogenesis, skeletal muscle, white adipose tissue, and brown adipose tissue.
Dependencies are inferred from the claim text.