Osmotic pump delivery system with flexible drug compartment

An implantable osmotic pump, comprising:

• a pump housing;
• an osmotic engines, the osmotic engine being disposed within the pump housing;
• a plurality of semipermeable membranes, each of the plurality of semipermeable membranes being configured to allow water to cross from a patient into the pump housing to the osmotic engine, and
• a flexible pharmaceutical agent compartment adapted to enclose a volume of pharmaceutical agent.

An implantable osmotic pump system, comprising:

• a rigid pump housing defining an opening;
• at least one membrane assembly fitted to the pump housing, the membrane assembly including a semipermeable membrane and an impermeable membrane initially sealing the semipermeable membrane and adapted to be breached by a lancet, the impermeable membrane being disposed away from the semipermeable membrane to define a fluid tight compartment, the fluid tight compartment enclosing a volume of an aqueous solution;
• an osmotic engine within the rigid pump housing, and
• a flexible pharmaceutical agent compartment disposed within the rigid pump housing, the flexible pharmaceutical agent compartment being in fluid communication with the opening.

An implantable osmotic pump system, comprising:

• a rigid pump housing defining an opening;
• at least one membrane assembly fitted to the pump housing, the membrane assembly including a semipermeable membrane and an impermeable membrane initially sealing the semipermeable membrane and adapted to be breached by a lancet, the impermeable membrane including a layer of one of gold, silver, platinum and platinum-iridium;
• an osmotic engine within the rigid pump housing, and
• a flexible pharmaceutical agent compartment disposed within the rigid pump housing, the flexible pharmaceutical agent compartment being in fluid communication with the opening.

An implantable osmotic pump system, comprising:

• a rigid pump housing defining an opening;
• a plurality of membrane assemblies fitted to the pump housing;
• an osmotic engine within the rigid pump housing, and
• a flexible pharmaceutical agent compartment disposed within the rigid pump housing, the flexible pharmaceutical agent compartment being in fluid communication with the opening.