Compositions and methods for the treatment of anorectal disorders
AssigneeCellergy Pharmaceuticals, Inc.
InventorsThomas P. Parks, Vivien Mak, Jung-Chung Lee, Charles Lee
Life of this patent
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Abstract
Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2−) scavengers, β-adrenergic agonists, cAMP-dependent protein kinase activators, α1-adrenergic antagonists, L-type Ca2+ channel blockers, estrogens, ATP-sensitive K+ channel activators and smooth muscle relaxants are used.
Claims17
A method of treating an anorectal disorder, and for controlling the pain associated therewith, the method comprising administering to a subject in need of such treatment a therapeutically effective amount of a topical composition comprising a cGMP modulating phosphodiesterase inhibitor.
A method of treating an anorectal disorder, and for controlling the pain associated therewith, the method comprising topically administering to a human subject in need of such treatment a PDE V phosphodiesterase inhibitor in a phosphodiesterase inhibitory therapeutic amount.
Dependencies are inferred from the claim text.