Thienopyrimidine compounds, their production and use
AssigneeTakeda Chemical Industries, Ltd.
InventorsShuichi Furuya, Nobuhiro Suzuki, Nobuo Choh, Yoshi Nara
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AssigneeTakeda Chemical Industries, Ltd.
InventorsShuichi Furuya, Nobuhiro Suzuki, Nobuo Choh, Yoshi Nara
Estimating the term…
A compound of formula (I) wherein R1 and R2 each is hydrogen, hydroxy, C1-4 alkoxy, C1-4 alkoxy-carbonyl or C1-4 alkyl which may be substituted; R3 is hydrogen, halogen, hydroxy or C1-4 alkoxy which may be substituted; or adjacent two R3 may form C1-4 alkylenedioxy; R4 is hydrogen or C1-4 alkyl; R6 is C1-4 alkyl which may be substituted or a group of the formula (A) wherein R5 is hydrogen of R4 and R5 may form heterocycle; and n is 0-5, or a salt thereof, has an excellent GnRH-antagonizing activity, and is useful for preventing or treating sex hormone-dependent diseases.
5-(N-Benzyl-N-methylaminomethyl)-1-(2,6-difluorobenzyl)-6-[4-(3-methoxyureido)phenyl]-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or a salt thereof.
Dependencies are inferred from the claim text.