Phospholipid complexes prepared from extracts of Vitis vinifera as anti-atherosclerotic agents
AssigneeIndena S.p.A.
InventorsPaolo Morazzoni, Ezio Bombardelli
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Abstract
The phospholipid complex extracts of Vitis vinifera useful for the prevention and the treatment of atherosclerotic pathological conditions and are administered to a patient in need of such treatment.
Claims10
A method for the treatment of atheosclersis or of myocardial or cerebral infarctions, which comprises administering a therapeutically effective amount of a phospholipid complex to a patient in need of such treatment, wherein the phospholipid complex is a complex resulting from the reaction of flavonoids extracted from Vitis vinifera with phospholipids selected from the group consisting of soy lecithin egg lecithin, phospholipids from bovine and porcine brains and skins, and compounds of the formula:
- in which R and R1, being identical or different, represent acyl groups from natural fatty acids and R2 represents (CH2)N+(CH3),(CH2)NH2, or CH2—CH(COOH)NH2, wherein the molar ratio of phospholipid to flavonoid is between 0.5 and 3.
Dependencies are inferred from the claim text.