System for the production of AAV vectors
AssigneeMediGene AG
InventorsChristoph Bogedain, Gerd Maass, Michael Hallek
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Abstract
The invention concerns a system comprising an AAV vector, which contains a foreign DNA, and rep 68/78 sequences of AAV with delayed expression, these sequences being present (a) in cis or (b) in trans. The invention also concerns the use of such a system for the production of AAV vectors.
Claims22
A system comprising an AAV vector containing a foreign DNA and rep 68/78 sequences of AAV with delayed expression, wherein these sequences are present (a) in cis or (b) in trans and are not integrated stably within cells.
A method for the production of AAV vectors, comprising expressing an AAV vector containing a foreign DNA and rep 68/78 sequences of AAV with delayed expression, wherein these sequences are present (a) in cis or (b) in trans and are not integrated stably within cells.
Dependencies are inferred from the claim text.