Isolated human metalloprotease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AssigneeApplera Corporation
InventorsGennady V. Merkulov, Jane Ye, Valentina Di Francesco, Ellen M. Beasley
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Abstract
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the protease peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the protease peptides, and methods of identifying modulators of the protease peptides.
Claims9
An isolated nucleic acid molecule consisting of a nucleotide sequence selected from the group consisting of:
- (a) a nucleotide sequence that encodes an amino acid sequence shown in SEQ ID NO:2;
- (b) a nucleic acid molecule consisting of the nucleic acid sequence of SEQ ID No:
- 1;
- (c) a nucleic acid molecule consisting of the nucleic acid sequence of SEQ ID No:
- 3;
- and
- (d) a nucleotide sequence that is completely complementary to a nucleotide sequence of (a)-(c).
An isolated polynucleotide consisting of a nucleotide sequence set forth in SEQ ID NO:1.
An isolated polynucleotide consisting of a nucleotide sequence set forth in SEQ ID NO:3.
Dependencies are inferred from the claim text.