US 6,294,359 B1 · Human basic fibroblast growth factor analog

Abstract

The DNA sequences encoding analogs of human acidic and basic fibroblast growth factors (FGF) can be recombinantly expressed to obtain practical amounts of proteins useful in effecting both pathologies related to persistent angiogenesis and wound healing and related tissue repair.

Claims6

Dependent claims

An isolated DNA molecule encoding a human basic fibroblast growth factor wherein the cysteine residues at positions 78 and 96 are replaced by serine residues.

Dependencies are inferred from the claim text.

Facts

Application

09/098,628Filed 16 Jun 1998 · division

Priority

12 Sep 1985

Granted

25 Sep 2001

Term ends

Not estimatedThe source records don’t support an estimate.

Classification14 codes

C12N 15/67
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression: general methods for enhancing…
A61K 38/1825
Growth factors; Growth regulators: fibroblast growth factor [FGF]
C07H 21/04
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of…: with…
C07K 14/50
Growth factors; Growth regulators: fibroblast growth factor [FGF]

Family

Application06/775,521Parent of this continuation-in-part · filed 12 Sep 1985

Application06/809,163Parent of this continuation-in-part · filed 16 Dec 1985

Application06/869,382Parent of this continuation-in-part · filed 30 May 1986

Application07/050,706Parent of this continuation-in-part · filed 15 May 1987

Application07/070,797Parent of this continuation-in-part · filed 7 Jul 1987

Application07/459,739Parent of this division · filed 12 Feb 1990

US 5,859,208 AParent of this division

Application07/459,739Parent of this continuation-in-part

US 5,439,818 AParent of this continuation-in-part

US 6,294,359 B1This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

09/098,628Filed 16 Jun 1998 · division

Priority

12 Sep 1985

Granted

25 Sep 2001

Term ends

Not estimatedThe source records don’t support an estimate.

Classification14 codes

C12N 15/67
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression: general methods for enhancing…
A61K 38/1825
Growth factors; Growth regulators: fibroblast growth factor [FGF]
C07H 21/04
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of…: with…
C07K 14/50
Growth factors; Growth regulators: fibroblast growth factor [FGF]

Family

Application06/775,521Parent of this continuation-in-part · filed 12 Sep 1985

Application06/809,163Parent of this continuation-in-part · filed 16 Dec 1985

Application06/869,382Parent of this continuation-in-part · filed 30 May 1986

Application07/050,706Parent of this continuation-in-part · filed 15 May 1987

Application07/070,797Parent of this continuation-in-part · filed 7 Jul 1987

Application07/459,739Parent of this division · filed 12 Feb 1990

US 5,859,208 AParent of this division

Application07/459,739Parent of this continuation-in-part

US 5,439,818 AParent of this continuation-in-part

US 6,294,359 B1This patent

From the US filing history. Foreign family members aren’t listed.

Human basic fibroblast growth factor analog

Life of this patent

Abstract

Claims6

Human basic fibroblast growth factor analog

Life of this patent

Abstract

Claims6