Method of treating a bacterial infection comprising administering amoxycillin
AssigneeBeecham Pharmaceuticals (Pte) Limited
InventorsCreighton P. Conley, John A. Roush, Kevin H. Storm
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Abstract
Bacterial infections may be treated using a high dosage regimen of amoxycillin. Preferably, the dosage is provided by a bilayer tablet.
Claims15
A method of treating a bacterial infection in a human in need thereof which method comprises administering to said human a dosage of a therepeutically effective amount of amoxycillin in the range of 1900 to 2600 mg, at a dosage regimen interval of about 12 h, and wherein the infection is caused by the organism S pneumoniae (including Drug Resistant and Penicillin Resistant S pneumoniae), H influenzae, M catarrhalis and/or S pyogenes.
A method of treating a bacterial infection in a human in need thereof which method comprises administering to said human a dosage of a therapeutically effective amount of amoxycillin in the range of 1400 to 1900 mg, at dosage regimen interval of about 12 h, such that the dosage regimen provides a mean plasma concentration of amoxycillin of 4 1μg/mL for at least 4.4 h, and a mean maximum plasma concentration (Cmax) of amoxycillin of at least 12 μg/mL.
Dependencies are inferred from the claim text.