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US 6,294,164 B1Granted
Natural killer cell enhancing factor C
AssigneeHuman Genome Sciences, Inc.
InventorsJiar Ni, Guo-Liang Yu, Reiner Gentz, Craig A. Rosen
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AssigneeHuman Genome Sciences, Inc.
InventorsJiar Ni, Guo-Liang Yu, Reiner Gentz, Craig A. Rosen
Estimating the term…
A human natural killer cell enhancing factor C and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating viral infections, inflammation, neoplasia and damage from superoxide radicals. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
An isolated polypeptide comprising at least 30 contiguous amino acid residues of SEQ ID NO:2.
An isolated polypeptide comprising at least 30 contiguous amino acid residues encoded by the cDNA in ATCC Deposit No. 97157.
An isolated polypepride comprising a first amino acid sequence 95% or more identical to a second amino acid sequence selected from the group consisting of:
An isolated polypeptide comprising a first amino acid sequence 95% or more identical to a second amino acid sequence selected from the group consisting of:
An isolated polypeptide comprising a fragment of SEQ ID NO:2, wherein said fragment has growth inhibitory activity.
An isolated polypeptide comprising a fragment of SEQ ID NO:2, wherein said fragment has anti-viral activity.
Dependencies are inferred from the claim text.