Solid dosage form with polymeric binder
AssigneeBASF SE
InventorsStephan Kothrade, Gunther Berndl, Helmut Meffert
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Abstract
The present invention relates to a solid dosage form comprising at least one polymeric binder and at least one active ingredient and, where appropriate, conventional additives, wherein the polymeric binder consists of copolymerized units a) 15-83% by weight of at least one N-vinyllactam, b) 15-83% by weight of methyl methacrylate, c) 2-70% by weight of at least one other monomer and d) 0-9.9% by weight of at least one α,β-ethylenically unsaturated acid.
Claims4
A solid dosage form comprising at least one polymeric binder, and at least one active ingredient wherein the polymeric binder consists essentially of copolymerization units of
- a) 30-65% by weight of at least one N-vinyllactam of the formula I
- in which n is 1,2, or 3,
- b) 20-55% by weight of methyl methacrylate,
- c) 15-50% by weight of at least one other monomer selected from vinyl esters of aliphatic C1-C22-carboxylic acids, esters of α, β-ethylenically unsaturated C3-C8-mono- and dicarboxylic acids wight C1-C8-alkanols, C1-C4-diols or di-(C1-C4-alkyamino-C1-C4-alkanols, amides, nitrites, and cyclic anhydrides of the carboxylic acids, and
- d) 0-5% by weight of at least on α, β-ethylenically unsaturated acid selected from C3-C8-mono- and -dicarboxylic acids, noncyclic anhydrides of these carboxylic acids, monoesters of the C3-C8-dicarboxylic acids, α, β-ethylenically unsaturated sulfonic acids and the salts or quaternized products thereof.
Dependencies are inferred from the claim text.