Semi-fluorinated alkanes and their use

A method for making a retinal tamponade, comprising dissolving a semi-fluorinated alkane of the general formula:

• RFRH or RFRHRF
• wherein RF is a linear or branched perfluoralkyl group and RH is a linear or branched, saturated alkyl group, wherein the linear semifluorinated alkane has the formula:
• F(CF2)n(CH2)mH or
• F(CF2)n(CH2)m(CF2)nF,
• the branched semifluorinated alkane includes within the perfluoralkyl groups —FCX— units where X=C2F5, C3F7 or C4F9 and within the alkyl groups —HCY— units where Y=C2H5, C3H7 or C4H9, contained within a perfluoralkyl chain is a —CX2— group and contained within an alkyl chain is a —CY2— group, and wherein further the total number of the carbon atoms in the perfluoralkyl part are between 3 and 20, and in the alkyl part the number of the carbon atoms is between 3 and 20 in a silicone oil.

A method for washing-out or diluting silicone oil in an eye which had a silicone oil retinal tamponade, comprising applying an effective amount of a semi-fluorinated alkane of the general formula

• RFRH or RFRHRF
• wherein RF is a linear or branched perfluoralkyl group and RH is a linear or branched, saturated alkyl group, wherein the linear semifluorinated alkane has the formula:
• F(CF2)n(CH2)mH or
• F(CF2)n(CH2)m (CF2)nF,
• the branched semifluorinated alkane includes within the perfluoralkyl groups —FCX— units where X=C2F5, C3F7 or C4F9 and within the alkyl groups —HCY— units where Y=C2H5, C3H7 or C4H9, contained within a perfluoralkyl chain is a —CX2— group and contained within an alkyl chain is a —CY2— group, and wherein further the total number of the carbon atoms in the perfluoralkyl part are between 3 and 20, and in the alkyl part the number of the carbon atoms is between 3 and 20 to said eye.

A method for the unfolding of a folded retina, comprising applying an effective amount of a semi-fluorinated alkane of the general formula

• RFRH or RFRHRF
• wherein RF is a linear or branched perfluoralkyl group and RH is a linear or branched, saturated alkyl group, wherein the linear semifluorinated alkane has the formula:
• F(CF2)n(CH2)mH or
• F(CF2)n(CH2)m(CF2)nF,
• the branched semifluorinated alkane includes within the perfluoralkyl groups —FCX— units where X=C2F5, C3F7 or C4F9 and within the alkyl groups —HCY— units where Y=C2H5, C3H7 or C4H9, contained within a perfluoralkyl chain is a —CX2— group and contained within an alkyl chain is a —CY2— group, and wherein further the total number of the carbon atoms in the perfluoralkyl part are between 3 and 20, and in the alkyl part the number of the carbon atoms is between 3 and 20.

A method for performing laser coagulation on the retina, comprising applying an effective amount of a semi-fluorinated alkane of the general formula

• RFRH or RFRHRF
• wherein RF is a linear or branched perfluoralkyl group and RH is a linear or branched, saturated alkyl group, wherein the linear semifluorinated alkane has the formula:
• F(CF2)n(CH2)mH or
• F(CF2)n(CH2)m(CF2)nF,
• the branched semifluorinated alkane includes within the Perfluoralkyl groups —FCX— units where X=C2F5, C3F7 or C4F9 and within the alkyl groups —HCY— units where Y=C2H5C3H7 or C4H9, contained within a perfluoralkyl chain is a —CX2— group and contained within an alkyl chain is a —CY2— group, and wherein further the total number of the carbon atoms in the perfluoralkyl part are between 3 and 20, and in the alkyl part the number of the carbon atoms is between 3 and 20 to the retina.