Parvovirus capsids
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsNeal S. Young, Sachiko Kajigaya, Takashi Shimada
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Abstract
The present invention relates to a method of producing non-infections parvovirus capsids and to diagnostic assays and vaccines utilizing same. The invention further relates to recombinant baculoviruses encoding parvovirus structural proteins and host cells infected therewith. The invention also relates to a method of packaging and delivering genetic information utilizing the noninfectious capsids.
Claims16
An immunogenic composition comprising:
- a pharmaceutically acceptable carrier and an immunogenically effective amount of empty B19 parvovirus capsids.
A composition for inducing neutralizing antibodies in a mammal, comprising a pharmaceutically acceptable carrier and an effective amount of empty B19 parvovirus capsids containing VP1 minor structural protein and VP2 major structural protein.
Dependencies are inferred from the claim text.