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AssigneeCSEM Centre Suisse d'Electronique et de Microtechnique SA
InventorsHui Chai-Gao, Reto Luginbuhl, Hans Sigrist, Nigel Skinner, Hendrik Van Den Vlekkert
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The invention relates to a device including a substrate and at least one biologically active substance bound to at least a part of the surface of this substrate, which is obtained by simultaneous or sequential reaction of said substrate and of said substance with a bifunctional coupling agent in which one of the functional groups is capable of being photoactivated and generates carbenes and is used to bind the coupling agent to the inorganic substrate and the other functional group is used to bind the coupling agent to the biologically active substance, in which said substrate is a covalent inorganic nitride.
A device including an inorganic substrate and at least one biologically active substance bound to at least a part of the surface of said substrate, said device being obtained by simultaneous or sequential reacting of said substrate and of said substance with a bifunctional coupling agent in which one of the functional groups has been photoactivated to generate carbenes that covalently bind the coupling agent to the inorganic substrate, and the other functional group binds the coupling agent to the biologically active substance, said substrate being a covalent inorganic nitride.
A method for binding a biologically active substance to a covalent inorganic nitride surface of a substrate, comprising the steps of reacting said surface with a bifunctional coupling agent by photoactivating one of the functional groups of said coupling agent to generate carbenes for covalently binding the coupling agent to said surface, and binding the biologically active substance to said coupling agent by the other functional group of said coupling agent.
Dependencies are inferred from the claim text.