Purified mammalian nucleobase permeases; nucleic acids; antibodies
AssigneeSchering Corporation
InventorsM. Jorge Guimaraes, J. Fernando Bazan, Terrill K. McClanahan, Albert Zlotnik
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Abstract
Nucleobase permeases from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids hybridizing to or encoding such proteins. Methods of making and using said reagents and diagnostic kits are also provided.
Claims25
A substantially pure or recombinant nucleic acid encoding a polypeptide comprising a plurality of non-overlapping segments of at least 8 amino acids from SEQ ID NO:
- 2.
A recombinant or isolated nucleic acid comprising a sequence exhibiting identity to a fragment of at least 30 nucleotides from nucleotidss 48-1880 of SEQ ID NO:
- 1.
A substantially pure or recombinant nucleic acid comprising a strand which hybridizes to nucleotides 48-1880 of SEQ ID NO:
- 1 at a temperature of at least 55.degree. C. and a salt concentration of less than 330 mM.
Dependencies are inferred from the claim text.