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AssigneeInnogenetics N.V.
InventorsRobert De Leys, Bart Vanderborght, Eric Saman, Hugo Van Heuverswyn
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Described is a new variety of retrovirus designated HIV-3, samples of which are deposited in the European Collection of Animal Cell Cultures (ECACC) under V88060301. Further described are antigens obtained from the virus, particularly proteins p12, p16, p25 and glycoproteins gp41 and gp120 to be used in the diagnosis of ARC or AIDS caused by HIV-3. The methods to detect antibodies against HIV-3 retrovirus in a biological fluid involve contacting the suspect body fluid with a composition containing one or more of the proteins or glycoproteins of HIV-3 or with a lysate of the virus, or with an antigen possessing epitopes common to HIV-3, and detecting the immunological conjugate formed between the anti-HIV-3 antibodies and the antigen(s) used.
A method for the detection of antibodies against HIV-3 retrovirus (also known as HIV-1 subtype O virus) in a biological fluid to assist in the diagnosis of a potential or existing ARC or AIDS caused by said HIV-3 retrovirus comprising:
A kit for the detection of anti-HIV-3-antibodies in a biological fluid comprising at least one isolated or purified antigen of HIV-3 retrovirus (also known as HIV-1 subtype O virus) (ECACC V88060301), a control sample, and reagents for detecting the immunological complex formed between the isolated or purified HIV-3 antigens, or the control sample, and the antibodies present in the biological sample.
Dependencies are inferred from the claim text.