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AssigneeYissum Research Development Company of the Hebrew University of Jerusalem
InventorsShlomo Magdassi, Zichria Zakay Rones, Moshe Linevitz, Oren Shanberg
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A pharmaceutical composition comprising an oil/water emulsion wherein the oil droplets contain a drug in dissolved or dispersed or solubilized form. The droplets are further coated with adsorbed native or modified antibodies which provide targeting of the droplets and the drug. The process for preparing this composition comprises the steps of (i) dissolving or dispersing a drug in an oil phase, (ii) preparing an oil/water emulsion, (iii) obtaining surface-active antibodies by chemical or physical attachment of hydrophobic groups to the antibodies, and (iv) mixing the surface-active antibody with the emulsion.
A pharmaceutical composition comprising an oil-in-water emulsion wherein the oil emulsion droplet contains dissolved or dispersed or solubilized a hydrophobic drug and on its surface absorbed antibodies which are modified by attaching hydrphobic groups wherein said composition is made by a process comprising the following steps:
A process for preparing a pharmaceutical composition which comprises an oil-in-water emulsion wherein the oil emulsion droplet contains dissolved or dispersed or solubilized a hydrophobic drug and on its surface adsorbed antibodies which are modified by attaching hydrophobic groups which comprises:
Dependencies are inferred from the claim text.