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US 5,858,357 AGranted
Pharmaceutical composition containing an isolated protease proenzyme, amylase, and aprotinin
OwnerFrantisek Trnka, Miroslav Rybak +2inventors
InventorsFrantisek Trnka, Miroslav Rybak, Roman Marek, Ladislav Vavra
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Abstract
The invention is directed to a pharmaceutical preparation with a modulatory effect on malignant tumors, which contains a combination of protease proenzymes and amylases in a ratio between 1:100 and 100:1 in enzymatic activity units, and a protease inhibitor. The invention is also directed to use of such a preparation to modulate the effects of malignant tumors in humans and animals.
Claims3
A pharmaceutical preparation with an inhibitory effect on malignant tumors, comprising:
- a malignant tumor inhibitory effective amount of a mixture of an isolated and inactive protease proenzyme selected from the group consisting of trypsinogen, chymotrypsinogen, proelastase, and prekallikrein;
- amylase;
- and
- aprotinin;
- wherein said protease proenzyme and said amylase are present in a ratio from 1:100 to 100:1 in units of enzymatic activity.
2 more elements
Dependencies are inferred from the claim text.