Parvovirus capsids
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsNeal S. Young, Sachiko Kajigaya, Takashi Shimada
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Abstract
The present invention relates to a method of producing non-infectious-parvovirus capsids and to diagnostic assays and vaccines utilizing same. The invention further relates to recombinant baculoviruses encoding parvovirus structural proteins and host cells infected therewith. The invention also relates to a method of packaging and delivering genetic information utilizing the noninfectious capsids.
Claims6
A diagnostic assay for the presence of antibodies to B19 parvovirus in a sample from a patient suspected of being infected with B19 parvovirus, the assay comprising:
- i) contacting the sample with isolated empty B19 parvovirus capsids, and
- ii) detecting the formation of an antigen antibody complex.
A diagnostic kit to detect the presence of antibodies to B19 parvovirus, comprising:
- i) isolated empty B19 parvovirus capsids, and
- ii) ancillary reagents.
Dependencies are inferred from the claim text.