Methods of use and compositions of R(-) fluoxetine
AssigneesSepracor Inc., The McLean Hospital Corporation
InventorsJames W. Young, Timothy J. Barberich, Martin H. Teicher
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Abstract
A method and composition are disclosed utilizing the pure R(-) isomer of fluoxetine which is a potent antidepressant and appetite suppressant substantially free of adverse effects. In addition, a method and composition are disclosed utilizing the pure R(-) isomer of fluoxetine which is useful to treat migraine headaches, pain, in particular chronic pain, psychoactive substance abuse disorders and obsessive compulsive disorders.
Claims20
A method of eliciting an antidepressant effect in a human which comprises administering to said human in need of antidepressant therapy an effective amount of R(-) fluoxetine, or a pharmaceutically acceptable salt thereof, substantially free of its S(+) stereoisomer.
A method of suppressing appetite in a human which comprises administering to said human in need of appetite suppression an effective amount of R(-) fluoxetine, or a pharmaceutically acceptable salt thereof, substantially free of its S(+) stereoisomer.
A method of treating pain in a human comprising administering to said human in need of such treatment an effective amount of R(-) fluoxetine, or a pharmaceutically acceptable salt thereof, substantially free of its S(+) stereoisomer.
A method of treating at least one psychoactive substance use disorder in a human which comprises administering an effective amount of R(-) fluoxetine, or a pharmaceutically acceptable salt thereof, substantially free of its S(+) stereoisomer.
A method of treating at least one obsessive compulsive disorder in a human which comprises administering an effective amount of R(-) fluoxetine, or a pharmaceutically acceptable salt thereof, substantially free of its S(+) stereoisomer.
Dependencies are inferred from the claim text.