US 5,708,030 AGranted

Substituted kynurenines and process for their preparation

AssigneesUniversity of Maryland, Pharmacia & Upjohn Company

InventorsRobert Schwarcz, Mario Varasi, Arturo Della Torre, Carmela Speciale, Alberto Bianchetti

Life of this patent

Estimating the term…

Abstract

The present invention relates to the use in the treatment of cognitive disorders associated with the aging processes of the brain and perinatal brain disorders of compounds which act as inhibitors of the enzyme kynurenine aminotransferase (KAT).

Claims3

Dependent claims

A method of treating age-related cognitive disorders and perinatal brain disorders comprising administering a therapeutically effective amount of an inhibitor of kynurenine aminotransferase (KAT) to a patient afflicted therewith.

Dependencies are inferred from the claim text.

Facts

Application: 08/463,895Filed 5 Jun 1995 · division
Priority: 6 Aug 1993
Granted: 13 Jan 1998
Term ends: Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07C 229/36
The carbon skeleton containing six-membered aromatic rings: with at least one amino group and one carboxyl group bound to the same carbon atom of…
A61K 31/00
Medicinal preparations containing organic active ingredients
A61K 31/165
Amides, e.g. hydroxamic acids: having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/195
Carboxylic acids, e.g. valproic acid: having an amino group

Family

Serial102,843Parent of this division · filed 6 Aug 1993
US 5,519,055 AParent of this division
US 5,708,030 AThis patent

From the US filing history. Foreign family members aren’t listed.

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