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US 5,708,024 AGranted
Salts of 2-(2,6-dichlorophenyl)amine!phenylacetoxyacetic acid with organic basic cations
AssigneeNovartis AG
InventorAlfred Sallmann
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AssigneeNovartis AG
InventorAlfred Sallmann
Estimating the term…
A salt of 2-(2,6-dichlorophenyl)amine!phenylacetoxyacetic acid with an organic basic cation of formula (I); Wherein R.sub.1 and R.sub.2 independently are lower alkyl, or if R.sub.1 is hydrogen H--N(R.sub.1)(R.sub.2) has the meaning of arginine or lysine or if R.sub.1 is methyl H--N(R.sub.1)(R.sub.2) has the meaning of N-methylglucamine. This compound pocesses analgesic activity as well as antiinflammatory activity, suitable in the treatment of conditions such as rheumatoid arthritis, ankylosing spondylitis, lumbar pains, luxations and ocular inflammation. The compound further has an improved stability in aqueous solutions in comparison to the alkali metal salts, e.g. sodium and potassium.
A salt of 2-(2,6-dichlorophenyl)amine!phenylacetoxyacetic acid with an organic basic cation of formula I ##STR5## wherein R.sub.1 and R.sub.2 independently are lower alkyl, or if R.sub.1 is hydrogen H--N(R.sub.1)(R.sub.2) has the meaning of arginine or lysine or if R.sub.1 is methyl H--N(R.sub.1)(R.sub.2) has the meaning of N-methylglucamine.
Dependencies are inferred from the claim text.