2,3-diaminopropionic acid derivative

A compound of the formula (1):

• ##STR215## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a cycloalkyl group, a lower alkenyl group, a lower alkynyl group, an aryl group, a heterocyclic group, a substituted lower alkyl group, a substituted cycloalkyl group, a substituted lower alkenyl group, a substituted lower alkynyl group, a substituted aryl group or a substituted heterocyclic group;
• R.sup.2 is a lower alkyl group, a cycloalkyl group, a lower alkenyl group, a lower alkynyl group, an aryl group, a heterocyclic group, a substituted lower alkyl group, a substituted cycloalkyl group, a substituted lower alkenyl group, a substituted lower alkynyl group, a substituted aryl group or a substituted heterocyclic group;
• V.sup.3 and V.sup.4 are the same or different and each a hydrogen atom, an alkyl group, a substituted lower alkyl group, a cycloalkyl group, an amino group, an acylamino group, a lower alkyloxycarbonyl group or a lower alkyloxycarbonyl group substituted by an aryl group;
• V.sup.5 is an imino group or an oxygen atom;
• V.sup.6 and V.sup.7 are a hydrogen atom or a lower alkyl group;
• A.sup.6 is a divalent group selected from the following groups:
• --(CH.sub.2).sub.f --CONR.sup.10 --CH.sub.2 --CHR.sup.9 -- (R.sup.9 and R.sup.10 are the same or different and each are a hydrogen atom or a lower alkyl group, f is 0 or 1);
• --Y.sup.4 --(CH.sub.2).sub.d -- (Y.sup.4 is an oxygen atom, and d is 3 or 4);
• --(CH.sub.2).sub.f --CO--(CH.sub.2).sub.d -- (f and d are the same as defined above);
• --(CH.sub.2).sub.f --CH(OH)--(CH.sub.2).sub.d -- (f and d are the same as defined above);
• --NR.sup.10 CO--(CH.sub.2).sub.d -- (R.sup.10 and d are the same as defined above);
• --Y.sup.4 --(CH.sub.2).sub.g --Y.sup.5 -- (Y.sup.4 is the same as defined above, Y.sup.5 is an oxygen atom or --NR.sup.11 -- (R.sup.11 is a hydrogen atom or a lower alkyl group), and g is 2 to 4);
• a group of the formula:
• ##STR216## wherein a is 1 or 2, and f is the same as defined above;
• a group of the formula:
• ##STR217## wherein f is the same as defined above, Y.sup.6 is a methine group or a nitrogen atom;
• a group of the formula:
• ##STR218## wherein Y.sup.5 and f are the same as defined above, and h is 0 or 1;
• a group of the formula:
• ##STR219## wherein Y.sup.4, Y.sup.5 and h are the same as defined above, or a pharmaceutically acceptable salt thereof.