Sulfated polysaccharids for treatment or prevention of thromboses
AssigneeRhone-Poulenc Rorer S.A.
InventorsJean-Pierre Baron, Andre Brun, Hendrik Hemker, Andre Uzan
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Abstract
The invention relates to new mixtures of sulfated oligosaccharides having the general structure of heparin constitutive oligosaccharides, having an average molecular mass of 6.+-.0.6 kD, a polydispersiveness close to 1 and the capacity of inhibiting the production of thrombin. The invention also relates to their preparation and to pharmaceutical compositions containing them.
Claims12
A mixture of sulfated oligosaccharides having the structure of constituent oligosaccharides of heparin, that has a mean molecular mass of 6.+-.0.6 kD and a polydispersity of 1 to 1.029, and that possesses a capacity to inhibit the generation of thrombin.
Dependencies are inferred from the claim text.