Nucleic acid encoding calf intestinal alkaline phosphatase
AssigneeLa Jolla Cancer Research Foundation
InventorJose L. Millan
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Abstract
The invention relates to isolated nucleic acids encoding recombinant calf intestinal alkaline phosphatase. Expression vectors and host cells transformed or transfected with such vectors are also provided. The invention further provides multifunctional polypeptides containing amino acid sequences encoding for calf intestinal alkaline phosphatase and a second amino acid sequence encoding a reagent having specific reactivity with a ligand. The recombinant calf intestinal alkaline phosphatase or its active fragments and the multifunctional polypeptides can be used in the methods for determining the presence or concentration of a ligand.
Claims9
An isolated nucleic acid having a nucleotide sequence as shown in FIG. 1 (SEQ ID NO:
- 9).
Dependencies are inferred from the claim text.