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US 5,707,836 AGranted
Production of alkylene or phenylenediamine disuccinic acid from fumaric acid and a diamine using lyase from microbes
AssigneeNitto Chemical Industry Co., Ltd.
InventorsTakakazu Endo, Yoshihiro Hashimoto, Rikiya Takahashi
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Abstract
A method of producing an optically active amino acid is disclosed which comprises converting a mixture of an amino group-containing compound, e.g., an alkanediamine, and fumaric acid into an optically active amino acid by the action of a microorganism. The method is useful in industrially producing an optically active amino acid from the inexpensive starting materials, i.e., fumaric acid and an amino compound, under mild conditions of ordinary temperature and ordinary pressure.
Claims12
A method of producing an optically active amino acid of formula (III):
- ##STR4## which comprises:
- treating a mixture of fumaric acid and an amino group-containing compound of formula (IV):
- H.sub.2 N-R.sub.5 -NH.sub.2 (IV)
- wherein R.sub.5 is an alkylene group, a cycloalkylene group or a phenylene group with a microorganism or treated cells thereof having a lyase activity which is able to convert a mixture of fumaric acid and the compound of formula (IV) into the optically active amino acid of formula (III), producing the compound of formula (III), and isolating the optically active amino acid of formula (III).
1 more element
Dependencies are inferred from the claim text.