US 5,707,646 A · Taste masking pharmaceutical composition

Abstract

A composition for oral preparations, having a complex formed by dispersing or dissolving an unpleasantly tasting basic drug and a functional polymer compound in a substance having a low melting point, 10 to 70% by weight, based on the composition, of sugar alcohol and 0.1 to 7% by weight, based on the composition, of basic oxide. The composition for oral preparation is excellent in masking unpleasantly tasting basic drugs and has excellent performance in biological use.

Claims9

Dependent claims

A composition for oral preparations, which comprises:

a) a complex formed by dispersing or dissolving an unpleasantly tasting basic drug and a functional polymer compound in a substance having a melting point of 40.degree. to 120.degree. C., wherein the functional polymer compound is selected from the group consisting of Eudragit.RTM. E, AEA (polyvinylacetal diethylaminoacetate) and mixtures thereof,
b) 10 to 70% by weight, based on the composition, of sugar alcohol, and
c) 0.1 to 7% by weight, based on the composition, of basic oxide.

Dependencies are inferred from the claim text.

Facts

Application

08/295,672Filed 9 Sep 1994

Priority

JP 4-05344212 Mar 1992

Granted

13 Jan 1998

Term ends

Not estimatedThe source records don’t support an estimate.

Classification4 codes

A61K 9/1617
Excipients; Inactive ingredients: organic compounds, e.g. phospholipids, fats
A61K 9/0095
Galenical forms not covered by A61K9/02 - A61K9/7023: drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets…
A61K 9/1635
Organic macromolecular compounds: obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, polyacrylates
A61K
Medicines and medical preparations

Taste masking pharmaceutical composition

Life of this patent

Taste masking pharmaceutical composition

Life of this patent

Abstract

Claims9