US 5,705,686 AGranted

Inhibition of farnesyl transferase

AssigneeUniversity of Pittsburgh

InventorsSaid Sebti, Andrew Hamilton

Life of this patent

Estimating the term…

Abstract

A compound of the formula C.sup.1 R where C.sup.1 is 3-mercapto-2-amino-propylamino and R is an aryl group. The compounds are useful for inhibiting p21ras farnesyltransferase.

Claims8

Dependent claims

A compound of the formula

C.sup.1 R
where C.sup.1 is 3-mercapto-2-amino-propylamino and R is biphenyl, optionally substituted with a carboxyl and/or alkyl moiety;
or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 08/371,682Filed 12 Jan 1995 · continuation in part
Priority: 18 May 1993
Granted: 6 Jan 1998
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

C07C 323/25
Having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton: the carbon skeleton being acyclic and saturated
C07C 323/59
With amino groups bound to the carbon skeleton: with acylated amino groups bound to the carbon skeleton
C07C 323/60
Having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton: with the carbon atom of at least one of the…
C07C 329/06
Esters of monothiocarbonic acids: having sulfur atoms of thiocarbonic groups bound to acyclic carbon atoms

Family

Serial62,287Parent of this continuation-in-part · filed 18 May 1993
US 5,602,098 AParent of this continuation-in-part
US 5,705,686 AThis patent

From the US filing history. Foreign family members aren’t listed.

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