Back to results
US 5,705,647 AGranted
Intermediates for making HIV-protease inhibitors
AssigneesAgouron Pharmaceuticals, Inc., Japan Tobacco Inc.
InventorsSrinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
Life of this patent
Estimating the term…
Abstract
HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
Claims4
A compound of formula 10:
- ##STR46## wherein R.sup.3 is aryl or alkyl;
- or a pharmaceutically acceptable salt or solvate thereof.
A compound of formula 8a:
- ##STR47## wherein R.sup.4 is alkyl;
- or a pharmaceutically acceptable salt or solvate thereof.
A compound of formula 9a:
- ##STR48## wherein R.sup.4 is alkyl;
- or a pharmaceutically acceptable salt or solvate thereof.
Dependencies are inferred from the claim text.