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US 5,705,626 AGranted
Cloned glutamic acid decarboxylase nucleic acids
AssigneeThe Regents of the University of California
InventorsAllan J. Tobin, Mark G. Erlander, Daniel L. Kaufman
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Abstract
The invention is directed to isolated polypeptides useful in ameliorating autoimmune disease.
Claims6
An isolated polynucleotide sequence encoding the polypeptide of the amino acid sequence:
- X-Pro-Glu-Val-Lys-Y-Lys-Z
- wherein X is an amino acid sequence selected from one to ten amino acids or omitted;
- Y is Glu;
- and Z is an amino acid sequence selected from one to eight amino acids or omitted wherein the polypeptide stimulates in vitro proliferation of human T lymphocytes.
1 more element
Dependencies are inferred from the claim text.