Fluoride ion releasing dental materials
AssigneeIndiana University Foundation
InventorsWilmer K. Fife, Martel Zeldin, Slawomir Rubinsztajn
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Abstract
Described are novel fluoride ion-releasing acrylic or methacrylic acid-based monomers, fluoride ion-releasing dental resin materials prepared from the monomers, and processes for preparing the monomers and dental resin materials. The monomers of the invention are prepared in good yield from readily available starting materials. Dental resin materials of the invention exhibit excellent sustained fluoride ion release.
Claims16
A dental resin material comprising a solid reaction product of a monomer of the formula:
- ##STR9## wherein Y.sup.- is a fluoride or fluoride-containing anion, R.sup.1 is --H or methyl, R.sup.2 is a divalent C.sub.1 -C.sub.12 alkylene radical, and each R.sup.3, which may be the same as or may differ from one another, is H, C.sub.1 -C.sub.16 alkyl or hydroxyalkyl, or a group of the formula ##STR10## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above, n is an integer from 1 to about 12, and each R.sup.4, which may be the same as or may differ from one another, is H, lower alkyl, lower hydroxyalkyl, or an amide group of the formula --CH(CH.sub.2 OH)(CONHCH.sub.2 CH.sub.2 OH);
- with at least one other polymerizable acrylic or methacrylic monomer, with the proviso that at least one of the reacted monomers is a free radical polymerizable crosslinking agent.
A dental resin material comprising a reaction product of a first monomer which is a fluoride ion-releasing polymerizable monomer bearing an anion exchange site carrying a fluoride-containing anion of the formula ((HF).sub.x F).sup.- wherein x is an integer from 1 to 7, with at least one other monomer which is an acrylic or methacrylic monomer, with the proviso that at least on of said monomers is a crosslinking monomer.
Dependencies are inferred from the claim text.