Pharmaceutical compositions of alkylsulphonamides 5HT1 agonists for rectal administration
AssigneeLaboratoires Glaxo SA
InventorsNadine Merlet, Isabelle Richard, Isabelle Thielemans
Life of this patent
Estimating the term…
Abstract
The present invention relates to a pharmaceutical composition for rectal administration in solid dosage form which comprises a compound acting as a 5HT-1 like receptor agonist in the form of its free base or a physiologically acceptable hard fat base carrier having a hydroxyl value of more than 15 in the method for the treament of a mammal suffering from a susceptible to conditions associated with cephalic pain.
Claims23
A pharmaceutical composition for rectal administration in solid dosage form which comprises an effective amount of a compound which acts as a 5HT.sub.1 -like receptor agonist in the form of its free base or a physiologically acceptable solvate thereof as active ingredient and a pharmaceutically acceptable hard fat base carrier having a Hydroxyl Value of more than 15.
A method for the treatment of a mammal, including man, suffering from or susceptible to conditions associated with cephalic pain such as cluster headache, chronic paroxysmal hemicrania, headache associated with vascular disorders, headache associated with substances or their withdrawal (for example drug withdrawal), tension headache and in particular migraine which comprises rectal administration of a pharmaceutical composition comprising a compound which acts as a 5HT.sub.1 -like receptor agonist in the form of its free base or a pharmaceutically acceptable solvate thereof.
Dependencies are inferred from the claim text.