Sulfamate derivatives of 1,3,5(10)-estratriene derivatives, methods for their production and pharmaceuticals containing these compounds

Sulfamate derivatives of the general formula I ##STR5## wherein R.sup.1 is a --CO--R.sup.3, --CO--OR.sup.4, --CO--NR.sup.5 R.sup.6, --SO.sub.2 --R.sup.4 or --SO.sub.2 --NU.sup.5 R.sup.6 group,

• in which
• R.sup.3 is a hydrogen atom or is as defined in R.sup.4,
• R.sup.4 represents a C.sub.1 -C.sub.5 alkyl residue, a C.sub.2 -C.sub.5 alkenyl residue, a C.sub.3 -C.sub.6 cycloalkyl residue or an aryl residue containing up to 9 carbon atoms,
• R.sup.5 and R.sup.6 are independent of each other and represent a hydrogen atom, a C.sub.1 -C.sub.5 alkyl residue, an aryl residue containing up to 9 carbon atoms, or, together with the N atom, represent a polymethylene imino residue containing 3 to 6 carbon atoms, or a morpholino residue,
• R.sup.2 is a hydrogen atom or a physiologically tolerable metal, or is as defined in R.sup.4,
• R.sup.7 and R.sup.8 are independent of each other and represent a hydrogen atom, a hydroxy group or a C.sub.1 -C.sub.5 alkoxy residue,
• R.sup.9 and R.sup.10 each represent a hydrogen atom, or together represent a methylene group,
• R.sup.11, R.sup.12 and R.sup.13 are independent of each other and represent a hydrogen atom or a hydroxy group that may optionally be esterified with physiologically tolerable inorganic or organic acids,
• or R.sup.12 or R.sup.13 is an alkinyl residue containing up to 5 carbon atoms,
• rings B and C may optionally contain one or two double bonds,
• and R.sup.8, R.sup.11 and R.sup.12 are independently placed either at the .alpha.- or .beta.-position.