Injectable compositions for soft tissue augmentation
AssigneeDatascope Investment Corp.
InventorsErnst Janzen, Matthias Johannes Hoekstra, Richard P. Dutrieux
Life of this patent
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Abstract
Injectable implant compositions for soft tissue augmentation comprise elastin and collagen and a biocompatible carrier. An injectable implant composition for soft tissue augmentation is derived from the ligamentum nuchae which has been treated to remove non-collagenous and non-elastinous proteins. Methods of making an injectable implant composition for soft tissue augmentation from the ligamentum nuchae are described.
Claims8
A method of treating urinary incontinence comprising the step of injecting a composition derived from animal tissue, comprising elastin and collagen and a biocompatible carrier into the area of the urethral sphincter, said tissue having been comminuted to break up the natural collagen/elastin matrix.
A method of breast augmentation comprising the step of injecting a composition derived from animal tissue, comprising elastin and collagen and a biocompatible carrier into the breast, said tissue having been comminuted to break up the natural collagen/elastin matrix.
A method of cosmetic treatment of wrinkles comprising the step of injecting a composition derived from animal tissue, comprising elastin and collagen and a biocompatible carrier into the soft tissue in or around the face, said tissue having been comminuted to break up the natural collagen/elastin matrix.
A method of load bearing tissue augmentation comprising the step of injecting a composition derived from animal tissue, comprising elastin and collagen and a biocompatible carrier between said load bearing tissue and a load-exerting medium, said tissue having been comminuted to break up the natural collagen/elastin matrix.
A method of treating acne scars or viral pock marks comprising the step of injecting a composition derived from animal tissue, comprising elastin and collagen and a biocompatible carrier into the soft tissue underlying said scar or pock mark, said tissue having been comminuted to break up the natural collagen/elastin matrix.
A method of changing the contours of a nose comprising the step of injecting a composition derived from animal tissue, comprising elastin and collagen and a biocompatible carrier into the soft tissue of the nose, said tissue having been comminuted to break up the natural collagen/elastin matrix.
A method of making an injectable implant composition derived from animal tissue, for soft tissue augmentation from ligamentum nuchae, said tissue having been comminuted to break up the natural collagen/elastin matrix, comprising the steps of
- washing the ligamentum nuchae in water,
- treating the washed ligamentum nuchae with a strong alkali solution,
- treating the resulting ligamentum nuchae with an acid,
- treating the acid-treated ligamentum nuchae with a base to neutralize the acid,
- mechanically working the neutralized ligamentum nuchae to separate collagen and elastin fibers, and
- suspending at least some of the collagen and elastin fibers in a suitable carrier.
A method of making an injectable implant composition derived from animal tissue for soft tissue augmentation, said tissue having been comminuted to break up the natural collagen/elastin matrix, comprising the steps of
- selecting tissue starting material from the group consisting of animal ligaments, tendons and membranes,
- washing said tissue in water,
- treating the washed tissue with a strong alkali solution,
- treating the resulting tissue with an acid,
- treating the acid-treated tissue with a base to neutralize the acid,
- mechanically working the neutralized tissue to separate elastin fibers, and
- suspending at least some of the elastin fibers in a suitable carrier.
Dependencies are inferred from the claim text.