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US 5,705,482 AGranted
Pharmaceutical formulation
AssigneeNovo Nordisk A/S
InventorsThorkild Christensen, Per Balschmidt, Hans Holmegaard S.o slashed.rensen, Ole Hvilsted Olsen, Lars Thim
Life of this patent
Estimating the term…
Abstract
A pharmaceutical formulation comprising a growth hormone and Leu-His-Leu as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.
Claims12
A pharmaceutical formulation comprising hGH and Leu-His-Leu.
Dependencies are inferred from the claim text.